Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
alkADNA-3-methyladenine glycosylase. (304 aa)    
Predicted Functional Partners:
ada
Ada protein (O6-methylguanine-DNA methyltransferase).
  
 
 0.878
Lcin_2684
uroporphyrin-III C- methyltransferase.
 
     0.823
sdhA-2
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
       0.756
sdhC-2
Succinate dehydrogenase, cytochrome b556 subunit.
       0.737
sdhD-2
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
       0.737
acnA_2
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
       0.723
dinP
DNA damage inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
   
 
 0.696
sdhB-2
Succinate dehydrogenase, iron sulfur protein.
       0.692
xthA
Exodeoxyribonuclease III.
   
 0.577
exoA
Exodeoxyribonuclease.
   
 0.577
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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