asnC protein (Legionella cincinnatiensis) - STRING interaction network

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asnC

DNA-binding transcriptional dual regulator. (158 aa)

Predicted Functional Partners:

lrp

0.767

asnA

0.740

thiDE

0.626

Lcin_1271

0.547

pdhB_1

0.528

trpE

0.447

indA

0.424

birA

0.413

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_1271	asnC	Lcin_1271	Lcin_2763	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	DNA-binding transcriptional dual regulator.	0.547
Lcin_1271	birA	Lcin_1271	Lcin_3083	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	0.507
Lcin_1271	lrp	Lcin_1271	Lcin_2318	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	AsnC family transcriptional regulator.	0.547
Lcin_1271	pdhB_1	Lcin_1271	Lcin_0188	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Pyruvate/2-oxoglutarate dehydrogenase subunit E1.	0.923
asnA	asnC	Lcin_2764	Lcin_2763	Asparagine synthetase A.	DNA-binding transcriptional dual regulator.	0.740
asnC	Lcin_1271	Lcin_2763	Lcin_1271	DNA-binding transcriptional dual regulator.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.547
asnC	asnA	Lcin_2763	Lcin_2764	DNA-binding transcriptional dual regulator.	Asparagine synthetase A.	0.740
asnC	birA	Lcin_2763	Lcin_3083	DNA-binding transcriptional dual regulator.	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	0.413
asnC	indA	Lcin_2763	Lcin_1713	DNA-binding transcriptional dual regulator.	AraC family transcriptional regulator; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.	0.424
asnC	lrp	Lcin_2763	Lcin_2318	DNA-binding transcriptional dual regulator.	AsnC family transcriptional regulator.	0.767
asnC	pdhB_1	Lcin_2763	Lcin_0188	DNA-binding transcriptional dual regulator.	Pyruvate/2-oxoglutarate dehydrogenase subunit E1.	0.528
asnC	thiDE	Lcin_2763	Lcin_1435	DNA-binding transcriptional dual regulator.	Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.626
asnC	trpE	Lcin_2763	Lcin_2925	DNA-binding transcriptional dual regulator.	Anthranilate synthase.	0.447
birA	Lcin_1271	Lcin_3083	Lcin_1271	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.507
birA	asnC	Lcin_3083	Lcin_2763	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	DNA-binding transcriptional dual regulator.	0.413
birA	indA	Lcin_3083	Lcin_1713	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	AraC family transcriptional regulator; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.	0.575
birA	lrp	Lcin_3083	Lcin_2318	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	AsnC family transcriptional regulator.	0.413
birA	pdhB_1	Lcin_3083	Lcin_0188	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	Pyruvate/2-oxoglutarate dehydrogenase subunit E1.	0.521
birA	thiDE	Lcin_3083	Lcin_1435	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.692
indA	asnC	Lcin_1713	Lcin_2763	AraC family transcriptional regulator; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.	DNA-binding transcriptional dual regulator.	0.424