STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asnAAsparagine synthetase A. (325 aa)    
Predicted Functional Partners:
asnB
Asparagine synthetase, glutamine-hydrolyzing.
   
 
 0.877
asg
L-asparaginase I.
     
 0.861
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.858
lysAC
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
     
 0.848
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.847
iaaA
Isoaspartyl dipeptidase with L-asparaginase activity.
     
  0.847
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
  0.847
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
  0.847
Lcin_2700
Aspartate aminotransferase.
     
 0.805
hemL
Glutamate-1-semialdehyde-2,1-aminomutase.
     
 0.759
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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