fda protein (Legionella cincinnatiensis) - STRING interaction network

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Score

fda

Fructose-bisphosphate aldolase. (336 aa)

Predicted Functional Partners:

gap

0.915

pgi

0.860

tpi

0.832

pgk

0.822

pfp

0.796

dmpP

0.790

tkt

0.775

pdhB_1

0.737

pykA

0.712

mdh

0.710

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dmpP	fda	Lcin_2794	Lcin_2793	ferredoxin-NADP reductase.	Fructose-bisphosphate aldolase.	0.790
fda	dmpP	Lcin_2793	Lcin_2794	Fructose-bisphosphate aldolase.	ferredoxin-NADP reductase.	0.790
fda	gap	Lcin_2793	Lcin_0110	Fructose-bisphosphate aldolase.	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.915
fda	mdh	Lcin_2793	Lcin_1214	Fructose-bisphosphate aldolase.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.	0.710
fda	pdhB_1	Lcin_2793	Lcin_0188	Fructose-bisphosphate aldolase.	Pyruvate/2-oxoglutarate dehydrogenase subunit E1.	0.737
fda	pfp	Lcin_2793	Lcin_2568	Fructose-bisphosphate aldolase.	PPi dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.	0.796
fda	pgi	Lcin_2793	Lcin_1401	Fructose-bisphosphate aldolase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.860
fda	pgk	Lcin_2793	Lcin_0109	Fructose-bisphosphate aldolase.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.822
fda	pykA	Lcin_2793	Lcin_0108	Fructose-bisphosphate aldolase.	Pyruvate kinase II; Belongs to the pyruvate kinase family.	0.712
fda	tkt	Lcin_2793	Lcin_0111	Fructose-bisphosphate aldolase.	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.775
fda	tpi	Lcin_2793	Lcin_0780	Fructose-bisphosphate aldolase.	Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.	0.832
gap	fda	Lcin_0110	Lcin_2793	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Fructose-bisphosphate aldolase.	0.915
gap	mdh	Lcin_0110	Lcin_1214	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.	0.834
gap	pdhB_1	Lcin_0110	Lcin_0188	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Pyruvate/2-oxoglutarate dehydrogenase subunit E1.	0.800
gap	pfp	Lcin_0110	Lcin_2568	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	PPi dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.	0.723
gap	pgi	Lcin_0110	Lcin_1401	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.929
gap	pgk	Lcin_0110	Lcin_0109	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.999
gap	pykA	Lcin_0110	Lcin_0108	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Pyruvate kinase II; Belongs to the pyruvate kinase family.	0.970
gap	tkt	Lcin_0110	Lcin_0111	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.949
gap	tpi	Lcin_0110	Lcin_0780	Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.	0.998