add_2 protein (Legionella cincinnatiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

add_2

Adenosine deaminase. (494 aa)

Predicted Functional Partners:

xapA

0.935

surE

0.852

add_1

0.848

yfiH

0.848

yjjG

0.698

Lcin_2810

0.683

hpt

0.634

Lcin_1985

0.618

Lcin_1897

0.576

Lcin_0328

0.568

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0328	add_1	Lcin_0328	Lcin_1965	3'-nucleotidase/nuclease.	Adenosine deaminase.	0.414
Lcin_0328	add_2	Lcin_0328	Lcin_2809	3'-nucleotidase/nuclease.	Adenosine deaminase.	0.568
Lcin_0328	xapA	Lcin_0328	Lcin_3281	3'-nucleotidase/nuclease.	Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.485
Lcin_1897	add_1	Lcin_1897	Lcin_1965	Phosphatase.	Adenosine deaminase.	0.576
Lcin_1897	add_2	Lcin_1897	Lcin_2809	Phosphatase.	Adenosine deaminase.	0.576
Lcin_1897	xapA	Lcin_1897	Lcin_3281	Phosphatase.	Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.428
Lcin_1985	add_1	Lcin_1985	Lcin_1965	Acid phosphatase, class B.	Adenosine deaminase.	0.485
Lcin_1985	add_2	Lcin_1985	Lcin_2809	Acid phosphatase, class B.	Adenosine deaminase.	0.618
Lcin_1985	xapA	Lcin_1985	Lcin_3281	Acid phosphatase, class B.	Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.559
Lcin_2810	add_2	Lcin_2810	Lcin_2809	Branched-chain amino acid ABC transporter substrate-binding protein.	Adenosine deaminase.	0.683
add_1	Lcin_0328	Lcin_1965	Lcin_0328	Adenosine deaminase.	3'-nucleotidase/nuclease.	0.414
add_1	Lcin_1897	Lcin_1965	Lcin_1897	Adenosine deaminase.	Phosphatase.	0.576
add_1	Lcin_1985	Lcin_1965	Lcin_1985	Adenosine deaminase.	Acid phosphatase, class B.	0.485
add_1	add_2	Lcin_1965	Lcin_2809	Adenosine deaminase.	Adenosine deaminase.	0.848
add_1	hpt	Lcin_1965	Lcin_0249	Adenosine deaminase.	Pyrimidine phosphoribosyl transferase.	0.809
add_1	surE	Lcin_1965	Lcin_2484	Adenosine deaminase.	Acid phosphatase SurE (Stationary phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.852
add_1	xapA	Lcin_1965	Lcin_3281	Adenosine deaminase.	Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.943
add_1	yfiH	Lcin_1965	Lcin_2836	Adenosine deaminase.	Laccase domain protein YfiH; Belongs to the multicopper oxidase YfiH/RL5 family.	0.848
add_1	yjjG	Lcin_1965	Lcin_0255	Adenosine deaminase.	Haloacid dehalogenase.	0.749
add_2	Lcin_0328	Lcin_2809	Lcin_0328	Adenosine deaminase.	3'-nucleotidase/nuclease.	0.568