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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fleRTwo-component response regulator. (437 aa)    
Predicted Functional Partners:
fleS
Sensor histidine kinase.
 0.977
fleN
Flagellar synthesis regulator.
 
 0.957
rpoN
RNA polymerase sigma-54 factor (sigma-L); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.952
cheA
Chemotaxis histidine kinase.
 
 0.945
evgS_2
Sensor histidine kinase.
  
0.911
fixL_2
Sensor histidine kinase/response regulator LuxN.
 
 
 0.898
arcB_1
Sensory histidine-kinase / response regulator.
 
 0.882
letS
Legionella transmission sensor LetS.
 
 0.875
flgD
Flagellar basal body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.871
arcB_4
Sensory box histidine kinase/response regulator.
 
0.869
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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