Lcin_2904 protein (Legionella cincinnatiensis)

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Score

Lcin_2904

HAD-superfamily hydrolase. (220 aa)

Predicted Functional Partners:

hisB

0.806

pgi

0.736

guaA

0.701

hisIE

0.700

hisG

0.695

yjeE

0.684

mdh_1

0.678

yjjG

0.670

ribD

0.659

glmS

0.644

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_2904	glmS	Lcin_2904	Lcin_0844	HAD-superfamily hydrolase.	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	0.644
Lcin_2904	guaA	Lcin_2904	Lcin_2940	HAD-superfamily hydrolase.	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.701
Lcin_2904	hisB	Lcin_2904	Lcin_2197	HAD-superfamily hydrolase.	Histidinol-phosphatase/imisazoleglycerol- phosphat e dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family.	0.806
Lcin_2904	hisG	Lcin_2904	Lcin_2194	HAD-superfamily hydrolase.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.	0.695
Lcin_2904	hisIE	Lcin_2904	Lcin_2201	HAD-superfamily hydrolase.	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	0.700
Lcin_2904	mdh_1	Lcin_2904	Lcin_2387	HAD-superfamily hydrolase.	Alcohol dehydrogenase.	0.678
Lcin_2904	pgi	Lcin_2904	Lcin_1401	HAD-superfamily hydrolase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.736
Lcin_2904	ribD	Lcin_2904	Lcin_2464	HAD-superfamily hydrolase.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.659
Lcin_2904	yjeE	Lcin_2904	Lcin_0708	HAD-superfamily hydrolase.	ATPase with strong ADP affinity.	0.684
Lcin_2904	yjjG	Lcin_2904	Lcin_0255	HAD-superfamily hydrolase.	Haloacid dehalogenase.	0.670
glmS	Lcin_2904	Lcin_0844	Lcin_2904	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	HAD-superfamily hydrolase.	0.644
glmS	guaA	Lcin_0844	Lcin_2940	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.497
glmS	pgi	Lcin_0844	Lcin_1401	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.767
guaA	Lcin_2904	Lcin_2940	Lcin_2904	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	HAD-superfamily hydrolase.	0.701
guaA	glmS	Lcin_2940	Lcin_0844	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	0.497
guaA	pgi	Lcin_2940	Lcin_1401	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.424
guaA	ribD	Lcin_2940	Lcin_2464	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.418
guaA	yjjG	Lcin_2940	Lcin_0255	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Haloacid dehalogenase.	0.684
hisB	Lcin_2904	Lcin_2197	Lcin_2904	Histidinol-phosphatase/imisazoleglycerol- phosphat e dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family.	HAD-superfamily hydrolase.	0.806
hisB	hisG	Lcin_2197	Lcin_2194	Histidinol-phosphatase/imisazoleglycerol- phosphat e dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.	0.999