STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcin_2945Pyridine nucleotide-disulfide oxidoreductase. (348 aa)    
Predicted Functional Partners:
Lcin_2944
Hypothetical protein.
       0.834
fadH
2,4-dienoyl-CoA reductase.
     
 0.613
Lcin_1831
Sphingomyelin phosphodiesterase.
  
     0.540
eptA_1
Sulfatase.
       0.535
Lcin_0484
Carboxymuconolactone decarboxylase.
 
  
  0.496
map_2
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
   
   0.491
atpG
H+-transporting ATP synthase chain gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
   
   0.482
Lcin_0917
Hypothetical protein.
  
     0.481
iraA
Small-molecule methyltransferase IraA.
  
     0.477
atpC
H+-transporting ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
   0.475
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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