gltB_2 protein (Legionella cincinnatiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

gltB_2

Glutamate synthase; Belongs to the glutamate synthase family. (499 aa)

Predicted Functional Partners:

fadH

0.968

guaA

0.781

ldh

0.724

argF

0.656

xylA

0.638

rkpA

0.597

putA

0.585

pksM

0.577

Lcin_1271

0.569

apc3

0.560

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_1271	fadH	Lcin_1271	Lcin_1616	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	2,4-dienoyl-CoA reductase.	0.884
Lcin_1271	gltB_2	Lcin_1271	Lcin_2950	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Glutamate synthase; Belongs to the glutamate synthase family.	0.569
Lcin_1271	ldh	Lcin_1271	Lcin_1915	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.884
Lcin_1271	pksM	Lcin_1271	Lcin_2790	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Polyketide synthase.	0.805
Lcin_1271	putA	Lcin_1271	Lcin_0053	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Bifunctional PutA protein (proline dehydrogenase/ delta-1-pyrroline-5-carboxylate dehydrogenase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.489
Lcin_1271	rkpA	Lcin_1271	Lcin_0960	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Type I polyketide synthase WcbR.	0.898
Lcin_1271	xylA	Lcin_1271	Lcin_1800	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Xylene monooxygenase.	0.848
apc3	fadH	Lcin_2894	Lcin_1616	Acetophenone carboxylase gamma subunit.	2,4-dienoyl-CoA reductase.	0.660
apc3	gltB_2	Lcin_2894	Lcin_2950	Acetophenone carboxylase gamma subunit.	Glutamate synthase; Belongs to the glutamate synthase family.	0.560
apc3	ldh	Lcin_2894	Lcin_1915	Acetophenone carboxylase gamma subunit.	Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.690
apc3	putA	Lcin_2894	Lcin_0053	Acetophenone carboxylase gamma subunit.	Bifunctional PutA protein (proline dehydrogenase/ delta-1-pyrroline-5-carboxylate dehydrogenase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.866
argF	fadH	Lcin_1772	Lcin_1616	Ornithine carbamoyltransferase.	2,4-dienoyl-CoA reductase.	0.674
argF	gltB_2	Lcin_1772	Lcin_2950	Ornithine carbamoyltransferase.	Glutamate synthase; Belongs to the glutamate synthase family.	0.656
argF	guaA	Lcin_1772	Lcin_2940	Ornithine carbamoyltransferase.	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.843
argF	ldh	Lcin_1772	Lcin_1915	Ornithine carbamoyltransferase.	Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.642
argF	pksM	Lcin_1772	Lcin_2790	Ornithine carbamoyltransferase.	Polyketide synthase.	0.483
argF	rkpA	Lcin_1772	Lcin_0960	Ornithine carbamoyltransferase.	Type I polyketide synthase WcbR.	0.759
argF	xylA	Lcin_1772	Lcin_1800	Ornithine carbamoyltransferase.	Xylene monooxygenase.	0.849
fadH	Lcin_1271	Lcin_1616	Lcin_1271	2,4-dienoyl-CoA reductase.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.884
fadH	apc3	Lcin_1616	Lcin_2894	2,4-dienoyl-CoA reductase.	Acetophenone carboxylase gamma subunit.	0.660