Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
araBL-arabinolactonase. (300 aa)    
Predicted Functional Partners:
gfo
Oxidoreductase.
 
 
 0.815
Lcin_2960
Amidohydrolase.
 
     0.731
Lcin_2121
Hypothetical protein.
    
 0.728
cycA
Cytochrome c.
  
  
 0.720
iolG
Myo-inositol 2-dehydrogenase.
 
 
 0.675
katA
Catalase; Belongs to the catalase family.
   
 
 0.616
pglA
Glycoside hydrolase family 28 protein / polygalacturonase; Belongs to the glycosyl hydrolase 28 family.
  
  
  0.600
rplQ
50S ribosomal protein L17.
 
      0.592
Lcin_0024
NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
  
 
 0.591
Lcin_0830
Oxidoreductase.
 
 
 0.575
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
Server load: medium (42%) [HD]