STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhThreonine(-3-)dehydrogenase. (345 aa)    
Predicted Functional Partners:
Lcin_0503
Saframycin Mx1 synthetase B.
  
 
 0.828
rkpA
Type I polyketide synthase WcbR.
  
 
0.817
Lcin_1271
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.781
pdhB_1
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
  
 
 0.779
xylA
Xylene monooxygenase.
  
 
 0.719
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.715
frmC
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 
 
 
 0.694
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional).
    
  0.668
frmA
Alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
0.640
mdh_1
Alcohol dehydrogenase.
  
 
 0.640
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
Server load: medium (44%) [HD]