STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcin_3068Mevalonate kinase. (293 aa)    
Predicted Functional Partners:
Lcin_3067
Diphosphomevalonate decarboxylase.
 
 
 0.992
mvaA
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.972
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.833
pal
Peptidoglycan-associated lipoprotein precursor (19 kDa surface antigen) (PPL); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
       0.624
ybgF
Outer membrane protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
       0.624
Lcin_1271
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
  0.581
Lcin_3063
Mammalian cell entry related domain protein.
       0.560
Lcin_3064
Transport protein.
       0.560
mlaE
ABC transporter permease.
       0.554
Lcin_3062
ABC transporter ATP-binding protein.
       0.554
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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