| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lcin_1937 | cysK | Lcin_1937 | Lcin_0974 | Phosphoserine phosphatase. | Cystathionine beta-synthase. | 0.680 |
| Lcin_1937 | glyA | Lcin_1937 | Lcin_1342 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.741 |
| Lcin_1937 | glyA_2 | Lcin_1937 | Lcin_1083 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase. | 0.675 |
| Lcin_1937 | lysAC | Lcin_1937 | Lcin_2376 | Phosphoserine phosphatase. | Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.736 |
| Lcin_1937 | metB | Lcin_1937 | Lcin_1359 | Phosphoserine phosphatase. | Cystathionine beta-lyase. | 0.680 |
| Lcin_1937 | sdhL | Lcin_1937 | Lcin_3088 | Phosphoserine phosphatase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.638 |
| Lcin_1937 | serC | Lcin_1937 | Lcin_3295 | Phosphoserine phosphatase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.833 |
| budB | lysAC | Lcin_1642 | Lcin_2376 | Acetolactate synthase; Belongs to the TPP enzyme family. | Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.474 |
| budB | pykA | Lcin_1642 | Lcin_0108 | Acetolactate synthase; Belongs to the TPP enzyme family. | Pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.661 |
| budB | sdhL | Lcin_1642 | Lcin_3088 | Acetolactate synthase; Belongs to the TPP enzyme family. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.676 |
| cysK | Lcin_1937 | Lcin_0974 | Lcin_1937 | Cystathionine beta-synthase. | Phosphoserine phosphatase. | 0.680 |
| cysK | glyA | Lcin_0974 | Lcin_1342 | Cystathionine beta-synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.516 |
| cysK | glyA_2 | Lcin_0974 | Lcin_1083 | Cystathionine beta-synthase. | Serine hydroxymethyltransferase. | 0.516 |
| cysK | lysAC | Lcin_0974 | Lcin_2376 | Cystathionine beta-synthase. | Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.770 |
| cysK | metB | Lcin_0974 | Lcin_1359 | Cystathionine beta-synthase. | Cystathionine beta-lyase. | 0.985 |
| cysK | sdhL | Lcin_0974 | Lcin_3088 | Cystathionine beta-synthase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.602 |
| cysK | serC | Lcin_0974 | Lcin_3295 | Cystathionine beta-synthase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.694 |
| gcvT | glyA | Lcin_2624 | Lcin_1342 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.986 |
| gcvT | glyA_2 | Lcin_2624 | Lcin_1083 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase. | 0.981 |
| gcvT | sdhL | Lcin_2624 | Lcin_3088 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.718 |