Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpxA_2Sensor histidine kinase. (456 aa)    
Predicted Functional Partners:
cpxR_2
Transcriptional regulatory protein CpxR.
 
 0.995
cpxR_3
Transcriptional regulatory protein CpxR.
 
 
 0.812
ompR
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 
 0.811
ybeY
Metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.804
cpxR_1
Transcriptional regulatory protein CpxR.
 
 
 0.802
Lsai_0327
Phosphate starvation-inducible protein PhoH.
  
  
 0.802
ybeX
Protein involved in divalent ion export.
       0.788
lrpR
DNA-binding response regulator.
 
 
 0.744
Lsai_3119
Sensory histidine-kinase / response regulator.
 
 
 
 0.715
Lsai_0985
Response regulator.
 
 
 0.710
Your Current Organism:
Legionella sainthelensi
NCBI taxonomy Id: 28087
Other names: ATCC 35248, CCUG 29672, CIP 103885, DSM 19231, L. sainthelensi, NCTC 11988, strain MSH-4, strain Mt. St. Helens 4
Server load: low (14%) [HD]