node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lsai_1059 | hemC | Lsai_1059 | Lsai_1058 | Acid-resistance membrane protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.666 |
Lsai_1059 | hemD | Lsai_1059 | Lsai_1057 | Acid-resistance membrane protein. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.666 |
Lsai_1059 | hemX | Lsai_1059 | Lsai_1056 | Acid-resistance membrane protein. | Uroporphyrinogen III methylase HemX. | 0.666 |
Lsai_1059 | hemY | Lsai_1059 | Lsai_1055 | Acid-resistance membrane protein. | Protoporphyrinogen oxidase. | 0.666 |
ccmC | hemA | Lsai_1280 | Lsai_1569 | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.409 |
ccmC | hemD | Lsai_1280 | Lsai_1057 | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.570 |
hemA | ccmC | Lsai_1569 | Lsai_1280 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.409 |
hemA | hemB | Lsai_1569 | Lsai_2920 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | 0.860 |
hemA | hemC | Lsai_1569 | Lsai_1058 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.980 |
hemA | hemD | Lsai_1569 | Lsai_1057 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.690 |
hemA | hemE | Lsai_1569 | Lsai_3138 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.629 |
hemA | hemL | Lsai_1569 | Lsai_3236 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.987 |
hemB | hemA | Lsai_2920 | Lsai_1569 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.860 |
hemB | hemC | Lsai_2920 | Lsai_1058 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.994 |
hemB | hemD | Lsai_2920 | Lsai_1057 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.873 |
hemB | hemE | Lsai_2920 | Lsai_3138 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.702 |
hemB | hemL | Lsai_2920 | Lsai_3236 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.992 |
hemC | Lsai_1059 | Lsai_1058 | Lsai_1059 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Acid-resistance membrane protein. | 0.666 |
hemC | hemA | Lsai_1058 | Lsai_1569 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.980 |
hemC | hemB | Lsai_1058 | Lsai_2920 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | 0.994 |