| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lsai_2422 | pepP | Lsai_2422 | Lsai_2423 | Hypothetical protein; Belongs to the UPF0149 family. | Proline aminopeptidase P II. | 0.762 |
| Lsai_2422 | ubiH | Lsai_2422 | Lsai_2424 | Hypothetical protein; Belongs to the UPF0149 family. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.762 |
| Lsai_2422 | visC | Lsai_2422 | Lsai_2425 | Hypothetical protein; Belongs to the UPF0149 family. | Oxidoreductase with FAD/NAD(P)-binding domain protein. | 0.762 |
| Lsai_2422 | zapA | Lsai_2422 | Lsai_2421 | Hypothetical protein; Belongs to the UPF0149 family. | Cell division protein ZapA. | 0.633 |
| grlA | ubiH | Lsai_0794 | Lsai_2424 | Glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.500 |
| grlA | visC | Lsai_0794 | Lsai_2425 | Glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Oxidoreductase with FAD/NAD(P)-binding domain protein. | 0.495 |
| pepP | Lsai_2422 | Lsai_2423 | Lsai_2422 | Proline aminopeptidase P II. | Hypothetical protein; Belongs to the UPF0149 family. | 0.762 |
| pepP | ubiH | Lsai_2423 | Lsai_2424 | Proline aminopeptidase P II. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.821 |
| pepP | visC | Lsai_2423 | Lsai_2425 | Proline aminopeptidase P II. | Oxidoreductase with FAD/NAD(P)-binding domain protein. | 0.821 |
| pepP | zapA | Lsai_2423 | Lsai_2421 | Proline aminopeptidase P II. | Cell division protein ZapA. | 0.624 |
| sspA | ubiH | Lsai_1083 | Lsai_2424 | Stringent starvation protein A. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.499 |
| sspA | visC | Lsai_1083 | Lsai_2425 | Stringent starvation protein A. | Oxidoreductase with FAD/NAD(P)-binding domain protein. | 0.573 |
| ubiA | ubiD | Lsai_0339 | Lsai_0820 | 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family. | 0.939 |
| ubiA | ubiG | Lsai_0339 | Lsai_0255 | 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.739 |
| ubiA | ubiH | Lsai_0339 | Lsai_2424 | 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.618 |
| ubiA | ubiX | Lsai_0339 | Lsai_1905 | 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.935 |
| ubiA | visC | Lsai_0339 | Lsai_2425 | 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Oxidoreductase with FAD/NAD(P)-binding domain protein. | 0.637 |
| ubiD | ubiA | Lsai_0820 | Lsai_0339 | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family. | 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.939 |
| ubiD | ubiH | Lsai_0820 | Lsai_2424 | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.568 |
| ubiD | ubiX | Lsai_0820 | Lsai_1905 | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.992 |