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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lsai_2467Methyltransferase involved in chemotaxis (CheR domain). (293 aa)    
Predicted Functional Partners:
Lsai_2464
Chemotaxis histidine kinase.
 
  
 0.998
cheB
Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 0.992
Lsai_2465
Chemotaxis signal transducer.
 
 
 0.978
Lsai_2466
Chemotaxis signal transduction protein (cheW domain).
 
  
 0.977
Lsai_2468
Chemotaxis signal transduction protein (cheW domain).
 
  
 0.956
Lsai_2462
Guanylate/adenylate cyclase.
 
   
 0.870
fliA
Sigma factor 28; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.869
Lsai_3119
Sensory histidine-kinase / response regulator.
  
 0.837
yjeK
Lysine aminomutase.
    
   0.828
Lsai_1901
Regulatory protein (GGDEF and EAL domains).
  
 0.821
Your Current Organism:
Legionella sainthelensi
NCBI taxonomy Id: 28087
Other names: ATCC 35248, CCUG 29672, CIP 103885, DSM 19231, L. sainthelensi, NCTC 11988, strain MSH-4, strain Mt. St. Helens 4
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