node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lsai_3000 | Lsai_3002 | Lsai_3000 | Lsai_3002 | Transmembrane protein. | Queuine tRNA-ribosyltransferase. | 0.513 |
Lsai_3000 | queA | Lsai_3000 | Lsai_3001 | Transmembrane protein. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.545 |
Lsai_3002 | Lsai_3000 | Lsai_3002 | Lsai_3000 | Queuine tRNA-ribosyltransferase. | Transmembrane protein. | 0.513 |
Lsai_3002 | Lsai_3003 | Lsai_3002 | Lsai_3003 | Queuine tRNA-ribosyltransferase. | Transmembrane protein. | 0.553 |
Lsai_3002 | guaA | Lsai_3002 | Lsai_0440 | Queuine tRNA-ribosyltransferase. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.549 |
Lsai_3002 | mip | Lsai_3002 | Lsai_1390 | Queuine tRNA-ribosyltransferase. | Macrophage infectivity potentiator. | 0.463 |
Lsai_3002 | queA | Lsai_3002 | Lsai_3001 | Queuine tRNA-ribosyltransferase. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.978 |
Lsai_3002 | queF | Lsai_3002 | Lsai_1022 | Queuine tRNA-ribosyltransferase. | GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.718 |
Lsai_3002 | ribA | Lsai_3002 | Lsai_0614 | Queuine tRNA-ribosyltransferase. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.427 |
Lsai_3002 | tgt | Lsai_3002 | Lsai_1064 | Queuine tRNA-ribosyltransferase. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.743 |
Lsai_3003 | Lsai_3002 | Lsai_3003 | Lsai_3002 | Transmembrane protein. | Queuine tRNA-ribosyltransferase. | 0.553 |
Lsai_3003 | queA | Lsai_3003 | Lsai_3001 | Transmembrane protein. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.524 |
guaA | Lsai_3002 | Lsai_0440 | Lsai_3002 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Queuine tRNA-ribosyltransferase. | 0.549 |
guaA | queF | Lsai_0440 | Lsai_1022 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.550 |
guaA | ribA | Lsai_0440 | Lsai_0614 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.581 |
guaA | tgt | Lsai_0440 | Lsai_1064 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.549 |
mip | Lsai_3002 | Lsai_1390 | Lsai_3002 | Macrophage infectivity potentiator. | Queuine tRNA-ribosyltransferase. | 0.463 |
mip | tgt | Lsai_1390 | Lsai_1064 | Macrophage infectivity potentiator. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.463 |
queA | Lsai_3000 | Lsai_3001 | Lsai_3000 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Transmembrane protein. | 0.545 |
queA | Lsai_3002 | Lsai_3001 | Lsai_3002 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Queuine tRNA-ribosyltransferase. | 0.978 |