Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lsai_3209Oxidoreductase,aldo/keto reductase family. (284 aa)    
Predicted Functional Partners:
ytbE
Aldo/keto reductase-like diketogulonate reductase.
  
     0.759
Lsai_0850
Oxidoreductase.
 
 
 0.657
Lsai_0940
Serine protein kinase.
   
    0.589
Lsai_0218
Aldo/keto reductase.
 
 
 0.553
Lsai_3210
3-hydroxyisobutyrate dehydrogenase.
       0.541
Lsai_3100
YcaC related amidohydrolase.
   
    0.436
Lsai_3169
Hypothetical protein.
  
    0.407
Your Current Organism:
Legionella sainthelensi
NCBI taxonomy Id: 28087
Other names: ATCC 35248, CCUG 29672, CIP 103885, DSM 19231, L. sainthelensi, NCTC 11988, strain MSH-4, strain Mt. St. Helens 4
Server load: low (18%) [HD]