Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIU17322.1Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)    
Predicted Functional Partners:
KIU17523.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
KIU17577.1
Enterobactin synthase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.982
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.961
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.939
KIU15948.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.937
KIU16726.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.913
KIU18813.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.907
KIU18810.1
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate.
  
 
 0.901
KIU18854.1
Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.889
KIU17526.1
Salicylate synthase MbtI; Catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.887
Your Current Organism:
Mycolicibacterium llatzerense
NCBI taxonomy Id: 280871
Other names: CCUG 54744, CECT 7273, DSM 45343, JCM 16229, M. llatzerense, Mycobacterium llatzerense, Mycobacterium llatzerense Gomila et al. 2008, Mycobacterium sp. 13-009-09768, Mycobacterium sp. MG12, Mycobacterium sp. MG13, Mycobacterium sp. MG14, Mycobacterium sp. MG15, Mycobacterium sp. MG16, Mycobacterium sp. MG18, Mycolicibacterium llatzerense (Gomila et al. 2008) Gupta et al. 2018, strain MG13
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