STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIU16054.1Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)    
Predicted Functional Partners:
KIU14532.1
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.890
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
 0.876
KIU17501.1
Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
  
  
 0.814
KIU16055.1
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.798
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.774
KIU18145.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.708
KIU18146.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.705
KIU18836.1
Peptidase S1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.702
hemL
Glutamate-1-semialdehyde aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.688
KIU18290.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.686
Your Current Organism:
Mycolicibacterium llatzerense
NCBI taxonomy Id: 280871
Other names: CCUG 54744, CECT 7273, DSM 45343, JCM 16229, M. llatzerense, Mycobacterium llatzerense, Mycobacterium llatzerense Gomila et al. 2008, Mycobacterium sp. 13-009-09768, Mycobacterium sp. MG12, Mycobacterium sp. MG13, Mycobacterium sp. MG14, Mycobacterium sp. MG15, Mycobacterium sp. MG16, Mycobacterium sp. MG18, Mycolicibacterium llatzerense (Gomila et al. 2008) Gupta et al. 2018, strain MG13
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