node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KIU14063.1 | KIU14883.1 | TL10_26530 | TL10_21795 | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.974 |
KIU14063.1 | KIU14898.1 | TL10_26530 | TL10_21915 | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.619 |
KIU14063.1 | KIU17330.1 | TL10_26530 | TL10_08145 | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | 0.610 |
KIU14063.1 | fbiC | TL10_26530 | TL10_05130 | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | FO synthase; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.525 |
KIU14063.1 | thiC | TL10_26530 | TL10_21920 | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.668 |
KIU14063.1 | thiE | TL10_26530 | TL10_21785 | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.697 |
KIU14063.1 | thiG | TL10_26530 | TL10_21800 | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.919 |
KIU14883.1 | KIU14063.1 | TL10_21795 | TL10_26530 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dinucleotide-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.974 |
KIU14883.1 | KIU14898.1 | TL10_21795 | TL10_21915 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.943 |
KIU14883.1 | KIU17330.1 | TL10_21795 | TL10_08145 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | 0.991 |
KIU14883.1 | fbiC | TL10_21795 | TL10_05130 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | FO synthase; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.871 |
KIU14883.1 | thiC | TL10_21795 | TL10_21920 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.892 |
KIU14883.1 | thiE | TL10_21795 | TL10_21785 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.981 |
KIU14883.1 | thiG | TL10_21795 | TL10_21800 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
KIU14896.1 | KIU14897.1 | TL10_21905 | TL10_21910 | Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |
KIU14896.1 | KIU14898.1 | TL10_21905 | TL10_21915 | Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.746 |
KIU14896.1 | thiC | TL10_21905 | TL10_21920 | Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.749 |
KIU14897.1 | KIU14896.1 | TL10_21910 | TL10_21905 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |
KIU14897.1 | KIU14898.1 | TL10_21910 | TL10_21915 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
KIU14897.1 | thiC | TL10_21910 | TL10_21920 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.893 |