| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KKB60890.1 | KKB62373.1 | WM40_26525 | WM40_17880 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.770 |
| KKB60890.1 | KKB62476.1 | WM40_26525 | WM40_17645 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.879 |
| KKB60890.1 | KKB62620.1 | WM40_26525 | WM40_16065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.868 |
| KKB60890.1 | KKB63217.1 | WM40_26525 | WM40_12905 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.770 |
| KKB60890.1 | KKB63414.1 | WM40_26525 | WM40_11785 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| KKB60890.1 | KKB64770.1 | WM40_26525 | WM40_04015 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Methionine biosynthesis protein MetW; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.725 |
| KKB60890.1 | glyA | WM40_26525 | WM40_09660 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.680 |
| KKB60890.1 | ilvA | WM40_26525 | WM40_00690 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.770 |
| KKB60890.1 | metX | WM40_26525 | WM40_04010 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Homoserine acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.852 |
| KKB60890.1 | metZ | WM40_26525 | WM40_07790 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.833 |
| KKB62373.1 | KKB60890.1 | WM40_17880 | WM40_26525 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.770 |
| KKB62373.1 | KKB62476.1 | WM40_17880 | WM40_17645 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.784 |
| KKB62373.1 | KKB62620.1 | WM40_17880 | WM40_16065 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.793 |
| KKB62373.1 | KKB63217.1 | WM40_17880 | WM40_12905 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.877 |
| KKB62373.1 | KKB63414.1 | WM40_17880 | WM40_11785 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.877 |
| KKB62373.1 | glyA | WM40_17880 | WM40_09660 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.898 |
| KKB62373.1 | ilvA | WM40_17880 | WM40_00690 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.895 |
| KKB62373.1 | metX | WM40_17880 | WM40_04010 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.728 |
| KKB62373.1 | metZ | WM40_17880 | WM40_07790 | Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.778 |
| KKB62476.1 | KKB60890.1 | WM40_17645 | WM40_26525 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.879 |