| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KKB61918.1 | KKB62016.1 | WM40_20235 | WM40_19775 | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.877 |
| KKB61918.1 | KKB64022.1 | WM40_20235 | WM40_08065 | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.898 |
| KKB61918.1 | KKB64111.1 | WM40_20235 | WM40_08070 | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.896 |
| KKB61918.1 | KKB64694.1 | WM40_20235 | WM40_04685 | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.912 |
| KKB61918.1 | KKB65192.1 | WM40_20235 | WM40_00605 | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 0.874 |
| KKB61918.1 | acsA | WM40_20235 | WM40_10925 | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | AMP-dependent synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.910 |
| KKB61918.1 | sucC | WM40_20235 | WM40_16615 | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.891 |
| KKB62016.1 | KKB61918.1 | WM40_19775 | WM40_20235 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 0.877 |
| KKB62016.1 | KKB64022.1 | WM40_19775 | WM40_08065 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.715 |
| KKB62016.1 | KKB64111.1 | WM40_19775 | WM40_08070 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.713 |
| KKB62016.1 | KKB64694.1 | WM40_19775 | WM40_04685 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.927 |
| KKB62016.1 | KKB65192.1 | WM40_19775 | WM40_00605 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 0.877 |
| KKB62016.1 | acsA | WM40_19775 | WM40_10925 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | AMP-dependent synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.888 |
| KKB62016.1 | sucC | WM40_19775 | WM40_16615 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.875 |
| KKB64022.1 | KKB61918.1 | WM40_08065 | WM40_20235 | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 0.898 |
| KKB64022.1 | KKB62016.1 | WM40_08065 | WM40_19775 | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.715 |
| KKB64022.1 | KKB64111.1 | WM40_08065 | WM40_08070 | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KKB64022.1 | KKB64694.1 | WM40_08065 | WM40_04685 | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.909 |
| KKB64022.1 | KKB65192.1 | WM40_08065 | WM40_00605 | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 0.515 |
| KKB64022.1 | acsA | WM40_08065 | WM40_10925 | succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.882 |