| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KKB61235.1 | KKB61236.1 | WM40_24360 | WM40_24365 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.997 |
| KKB61235.1 | KKB62865.1 | WM40_24360 | WM40_14845 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
| KKB61235.1 | KKB63095.1 | WM40_24360 | WM40_13985 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.867 |
| KKB61235.1 | KKB63522.1 | WM40_24360 | WM40_10930 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.540 |
| KKB61235.1 | acnA | WM40_24360 | WM40_07925 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.801 |
| KKB61235.1 | fumC | WM40_24360 | WM40_17510 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.894 |
| KKB61235.1 | glcB | WM40_24360 | WM40_02535 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.593 |
| KKB61235.1 | mdh | WM40_24360 | WM40_07910 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.859 |
| KKB61235.1 | sdhB | WM40_24360 | WM40_07885 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
| KKB61235.1 | sucC | WM40_24360 | WM40_16615 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.988 |
| KKB61236.1 | KKB61235.1 | WM40_24365 | WM40_24360 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| KKB61236.1 | KKB62865.1 | WM40_24365 | WM40_14845 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| KKB61236.1 | KKB63095.1 | WM40_24365 | WM40_13985 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.607 |
| KKB61236.1 | KKB63522.1 | WM40_24365 | WM40_10930 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.404 |
| KKB61236.1 | acnA | WM40_24365 | WM40_07925 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.428 |
| KKB61236.1 | fumC | WM40_24365 | WM40_17510 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.476 |
| KKB61236.1 | glcB | WM40_24365 | WM40_02535 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.887 |
| KKB61236.1 | mdh | WM40_24365 | WM40_07910 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.616 |
| KKB61236.1 | sdhB | WM40_24365 | WM40_07885 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.835 |
| KKB61236.1 | sucC | WM40_24365 | WM40_16615 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.984 |
