| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KKB61236.1 | KKB61987.1 | WM40_24365 | WM40_20165 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
| KKB61236.1 | KKB63385.1 | WM40_24365 | WM40_11570 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.875 |
| KKB61236.1 | KKB63813.1 | WM40_24365 | WM40_08960 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.445 |
| KKB61236.1 | KKB64295.1 | WM40_24365 | WM40_07505 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.850 |
| KKB61236.1 | acsA | WM40_24365 | WM40_10925 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | AMP-dependent synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.891 |
| KKB61267.1 | KKB61987.1 | WM40_24155 | WM40_20165 | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.822 |
| KKB61267.1 | KKB61996.1 | WM40_24155 | WM40_20155 | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.457 |
| KKB61267.1 | KKB64295.1 | WM40_24155 | WM40_07505 | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
| KKB61986.1 | KKB61987.1 | WM40_20160 | WM40_20165 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
| KKB61986.1 | KKB61996.1 | WM40_20160 | WM40_20155 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| KKB61987.1 | KKB61236.1 | WM40_20165 | WM40_24365 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.823 |
| KKB61987.1 | KKB61267.1 | WM40_20165 | WM40_24155 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | 0.822 |
| KKB61987.1 | KKB61986.1 | WM40_20165 | WM40_20160 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
| KKB61987.1 | KKB61996.1 | WM40_20165 | WM40_20155 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| KKB61987.1 | KKB63385.1 | WM40_20165 | WM40_11570 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.931 |
| KKB61987.1 | KKB63598.1 | WM40_20165 | WM40_10755 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | 0.822 |
| KKB61987.1 | KKB63662.1 | WM40_20165 | WM40_10015 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. | 0.893 |
| KKB61987.1 | KKB63813.1 | WM40_20165 | WM40_08960 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.885 |
| KKB61987.1 | KKB64295.1 | WM40_20165 | WM40_07505 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
| KKB61987.1 | acsA | WM40_20165 | WM40_10925 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.845 |