SMF53221.1 protein (Trinickia caryophylli) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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[Homology]

Score

SMF53221.1

Amino acid adenylation domain-containing protein. (515 aa)

Predicted Functional Partners:

SMF83447.1

0.999

SMF83589.1

0.999

SMF83721.1

0.999

SMF82474.1

0.998

SMF84171.1

0.998

SMF28527.1

0.997

SMF55666.1

0.995

SMF53209.1

0.987

SMF81952.1

0.985

SMF83454.1

0.981

Your Current Organism:

Trinickia caryophylli

NCBI taxonomy Id: 28094
Other names: ATCC 25418, Burkholderia caryophylli, CCUG 20834, CFBP 2429, CFBP 3818, CIP 105770, DSM 50341, HAMBI 2159, ICMP 512, JCM 10488, JCM 9310, LMG 2155, LMG:2155, NCPPB 2151, Paraburkholderia caryophylli, Phytomonas caryophylli, Pseudomonas caryophylli, Pseudomonas caryophyllii, T. caryophylli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SMF28527.1	SMF53209.1	SAMN06295900_1051	SAMN06295900_109100	Thioesterase domain-containing protein.	Phosphopantetheine attachment site.	0.999
SMF28527.1	SMF53221.1	SAMN06295900_1051	SAMN06295900_109101	Thioesterase domain-containing protein.	Amino acid adenylation domain-containing protein.	0.997
SMF28527.1	SMF55666.1	SAMN06295900_1051	SAMN06295900_11073	Thioesterase domain-containing protein.	Acyl transferase domain-containing protein.	0.999
SMF28527.1	SMF81952.1	SAMN06295900_1051	SAMN06295900_12438	Thioesterase domain-containing protein.	AMP-binding enzyme.	0.998
SMF28527.1	SMF82474.1	SAMN06295900_1051	SAMN06295900_12622	Thioesterase domain-containing protein.	Non-ribosomal peptide synthase domain TIGR01720.	0.999
SMF28527.1	SMF83447.1	SAMN06295900_1051	SAMN06295900_1331	Thioesterase domain-containing protein.	HxxPF-repeated domain-containing protein.	0.999
SMF28527.1	SMF83454.1	SAMN06295900_1051	SAMN06295900_1332	Thioesterase domain-containing protein.	Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.	0.999
SMF28527.1	SMF83589.1	SAMN06295900_1051	SAMN06295900_1361	Thioesterase domain-containing protein.	AMP-binding enzyme.	0.999
SMF28527.1	SMF83721.1	SAMN06295900_1051	SAMN06295900_1381	Thioesterase domain-containing protein.	AMP-binding enzyme.	0.999
SMF28527.1	SMF84171.1	SAMN06295900_1051	SAMN06295900_1481	Thioesterase domain-containing protein.	Amino acid adenylation domain-containing protein.	0.999
SMF53209.1	SMF28527.1	SAMN06295900_109100	SAMN06295900_1051	Phosphopantetheine attachment site.	Thioesterase domain-containing protein.	0.999
SMF53209.1	SMF53221.1	SAMN06295900_109100	SAMN06295900_109101	Phosphopantetheine attachment site.	Amino acid adenylation domain-containing protein.	0.987
SMF53209.1	SMF55666.1	SAMN06295900_109100	SAMN06295900_11073	Phosphopantetheine attachment site.	Acyl transferase domain-containing protein.	0.999
SMF53209.1	SMF81952.1	SAMN06295900_109100	SAMN06295900_12438	Phosphopantetheine attachment site.	AMP-binding enzyme.	0.959
SMF53209.1	SMF82474.1	SAMN06295900_109100	SAMN06295900_12622	Phosphopantetheine attachment site.	Non-ribosomal peptide synthase domain TIGR01720.	0.998
SMF53209.1	SMF83447.1	SAMN06295900_109100	SAMN06295900_1331	Phosphopantetheine attachment site.	HxxPF-repeated domain-containing protein.	0.999
SMF53209.1	SMF83454.1	SAMN06295900_109100	SAMN06295900_1332	Phosphopantetheine attachment site.	Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.	0.999
SMF53209.1	SMF83589.1	SAMN06295900_109100	SAMN06295900_1361	Phosphopantetheine attachment site.	AMP-binding enzyme.	0.999
SMF53209.1	SMF83721.1	SAMN06295900_109100	SAMN06295900_1381	Phosphopantetheine attachment site.	AMP-binding enzyme.	0.999
SMF53209.1	SMF84171.1	SAMN06295900_109100	SAMN06295900_1481	Phosphopantetheine attachment site.	Amino acid adenylation domain-containing protein.	0.999

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Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.908

expected number of edges:

10

PPI enrichment p-value:

9.44e-14

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006011

UDP-glucose metabolic process

2 of 2

2.27

0.91

0.0211

GO:0009225

Nucleotide-sugar metabolic process

3 of 12

1.66

0.89

0.0160

GO:0005975

Carbohydrate metabolic process

8 of 163

0.96

0.87

0.00026

GO:0000271

Polysaccharide biosynthetic process

4 of 35

1.32

0.78

0.0160

GO:0005978

Glycogen biosynthetic process

2 of 4

1.97

0.78

0.0331

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016779

Nucleotidyltransferase activity

5 of 42

1.34

1.14

0.0012

GO:0008878

glucose-1-phosphate adenylyltransferase activity

2 of 2

2.27

0.75

0.0421

GO:0003983

UTP:glucose-1-phosphate uridylyltransferase activity

2 of 2

2.27

0.75

0.0421

GO:0004645

1,4-alpha-oligoglucan phosphorylase activity

2 of 3

2.09

0.74

0.0421

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031470

Carboxysome

2 of 2

2.27

0.98

0.0154

GO:0045121

Membrane raft

2 of 5

1.87

0.91

0.0178

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2250

Starch and sucrose metabolism, and Alpha-amylase domain

6 of 24

1.66

2.32

1.22e-06

CL:2282

Glycogen metabolic process

3 of 5

2.04

1.71

0.00043

CL:2034

Mixed, incl. Carbohydrate transport, and Microbial metabolism in diverse environments

7 of 132

0.99

0.94

0.00014

CL:2032

Carbohydrate transport, and Carbohydrate metabolic process

8 of 166

0.95

0.91

7.39e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

lagl00500

Starch and sucrose metabolism

7 of 26

1.7

3.01

4.31e-09

lagl00520

Amino sugar and nucleotide sugar metabolism

6 of 26

1.63

2.48

1.84e-07

lagl00052

Galactose metabolism

4 of 10

1.87

2.23

1.38e-05

lagl00541

O-Antigen nucleotide sugar biosynthesis

4 of 11

1.83

2.19

1.41e-05

lagl00040

Pentose and glucuronate interconversions

2 of 3

2.09

1.29

0.0035

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0010170

glucose-1-phosphate adenylyltransferase complex

2 of 2

2.27

0.8

0.0331

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0548

Nucleotidyltransferase

5 of 26

1.55

1.73

4.38e-05

KW-0119

Carbohydrate metabolism

3 of 14

1.6

1.03

0.0066

KW-0808

Transferase

7 of 240

0.73

0.52

0.0066

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF12804

MobA-like NTP transferase domain

4 of 5

2.17

2.39

1.90e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005835

Nucleotidyl transferase domain

5 of 5

2.27

3.26

3.06e-07

IPR029044

Nucleotide-diphospho-sugar transferases

5 of 21

1.64

1.85

3.84e-05

IPR011832

Glucose-1-phosphate adenylyltransferase, GlgD subunit

2 of 2

2.27

0.76

0.0411

IPR011831

Glucose-1-phosphate adenylyltransferase

2 of 2

2.27

0.76

0.0411

IPR005771

UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type

2 of 2

2.27

0.76

0.0411

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