SMF65584.1 protein (Trinickia caryophylli) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

SMF65584.1

BON domain-containing protein. (196 aa)

Predicted Functional Partners:

SMF22995.1

0.711

SMF68866.1

0.711

SMF65572.1

0.541

SME94140.1

0.449

SMF33578.1

0.414

SMF65714.1

0.409

SMF79774.1

0.409

SME95097.1

0.405

SME97692.1

0.405

SMF15754.1

0.405

Your Current Organism:

Trinickia caryophylli

NCBI taxonomy Id: 28094
Other names: ATCC 25418, Burkholderia caryophylli, CCUG 20834, CFBP 2429, CFBP 3818, CIP 105770, DSM 50341, HAMBI 2159, ICMP 512, JCM 10488, JCM 9310, LMG 2155, LMG:2155, NCPPB 2151, Paraburkholderia caryophylli, Phytomonas caryophylli, Pseudomonas caryophylli, Pseudomonas caryophyllii, T. caryophylli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SME94140.1	SMF65584.1	SAMN06295900_101176	SAMN06295900_11439	Catalase; Belongs to the catalase family.	BON domain-containing protein.	0.449
SME94140.1	SMF65714.1	SAMN06295900_101176	SAMN06295900_11451	Catalase; Belongs to the catalase family.	Organic hydroperoxide reductase OsmC/OhrA.	0.466
SME94140.1	SMF79774.1	SAMN06295900_101176	SAMN06295900_12194	Catalase; Belongs to the catalase family.	Peroxiredoxin, Ohr subfamily.	0.496
SME95097.1	SMF22995.1	SAMN06295900_101266	SAMN06295900_104142	Hypothetical protein.	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	0.405
SME95097.1	SMF65584.1	SAMN06295900_101266	SAMN06295900_11439	Hypothetical protein.	BON domain-containing protein.	0.405
SME97692.1	SMF22995.1	SAMN06295900_101480	SAMN06295900_104142	Hypothetical protein.	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	0.405
SME97692.1	SMF65584.1	SAMN06295900_101480	SAMN06295900_11439	Hypothetical protein.	BON domain-containing protein.	0.405
SME97692.1	SMF68866.1	SAMN06295900_101480	SAMN06295900_115111	Hypothetical protein.	Protein of unknown function.	0.725
SMF15754.1	SMF22995.1	SAMN06295900_103246	SAMN06295900_104142	Hypothetical protein.	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	0.405
SMF15754.1	SMF65584.1	SAMN06295900_103246	SAMN06295900_11439	Hypothetical protein.	BON domain-containing protein.	0.405
SMF15754.1	SMF68866.1	SAMN06295900_103246	SAMN06295900_115111	Hypothetical protein.	Protein of unknown function.	0.725
SMF22995.1	SME95097.1	SAMN06295900_104142	SAMN06295900_101266	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	Hypothetical protein.	0.405
SMF22995.1	SME97692.1	SAMN06295900_104142	SAMN06295900_101480	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	Hypothetical protein.	0.405
SMF22995.1	SMF15754.1	SAMN06295900_104142	SAMN06295900_103246	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	Hypothetical protein.	0.405
SMF22995.1	SMF65584.1	SAMN06295900_104142	SAMN06295900_11439	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	BON domain-containing protein.	0.711
SMF22995.1	SMF65714.1	SAMN06295900_104142	SAMN06295900_11451	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	Organic hydroperoxide reductase OsmC/OhrA.	0.712
SMF22995.1	SMF68866.1	SAMN06295900_104142	SAMN06295900_115111	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	Protein of unknown function.	0.939
SMF22995.1	SMF79774.1	SAMN06295900_104142	SAMN06295900_12194	Uncharacterized conserved protein YjbJ, UPF0337 family; Belongs to the UPF0337 (CsbD) family.	Peroxiredoxin, Ohr subfamily.	0.712
SMF33578.1	SMF65584.1	SAMN06295900_105371	SAMN06295900_11439	Trehalose synthase.	BON domain-containing protein.	0.414
SMF65572.1	SMF65584.1	SAMN06295900_11438	SAMN06295900_11439	Hypothetical protein.	BON domain-containing protein.	0.541

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Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.922

expected number of edges:

17

PPI enrichment p-value:

2.65e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0010467

Gene expression

9 of 212

1.14

1.4

6.58e-07

GO:0009451

RNA modification

4 of 48

1.44

0.94

0.0075

GO:0006396

RNA processing

4 of 65

1.3

0.88

0.0078

GO:0006412

Translation

5 of 118

1.14

0.79

0.0075

GO:0044260

Cellular macromolecule metabolic process

7 of 468

0.69

0.46

0.0144

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

5 of 55

1.47

1.4

0.00033

GO:0019843

rRNA binding

3 of 42

1.37

0.61

0.0497

GO:0003723

RNA binding

4 of 98

1.13

0.58

0.0405

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

5 of 59

1.44

1.54

8.08e-05

GO:0005622

Intracellular anatomical structure

11 of 1310

0.44

0.37

0.00066

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4661

Mixed, incl. RNA (guanine-N7)-methylation, and Ferrous iron transport protein B

3 of 5

2.29

2.1

9.57e-05

CL:147

Structural constituent of ribosome

5 of 40

1.61

1.93

1.68e-05

CL:123

Ribonucleoprotein, and RNA metabolic process

8 of 139

1.27

1.65

7.50e-07

CL:374

Mixed, incl. Heat shock protein binding, and Peptidyl-proline modification

2 of 5

2.12

1.16

0.0064

CL:151

rRNA-binding, and Elongation factor G C-terminus

3 of 29

1.53

1.09

0.0040

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

5 of 60

1.44

1.52

8.53e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005622

Intracellular

11 of 1403

0.41

0.31

0.0093

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 60

1.44

1.46

0.00015

KW-0699

rRNA-binding

3 of 39

1.4

0.81

0.0163

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