STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1029 aa)    
Predicted Functional Partners:
AMN10138.1
DNA repair nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.961
AMN10139.1
Recombinase RecA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.956
dnaX
DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.882
holA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.866
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.857
dnaQ
DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
    
 
 0.857
holB
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.857
ssb
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.856
AMN12888.1
DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.853
AMN13838.1
DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.586
Your Current Organism:
Alteromonas macleodii
NCBI taxonomy Id: 28108
Other names: A. macleodii, ATCC 27126, Alteromonas sp. F12, CCUG 16128, CIP 103198, DSM 6062, JCM 20772, LMG 2843, LMG:2843, NBRC 102226, Pseudoalteromonas macleodii
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