node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lxx04460 | dnaN | Lxx04460 | Lxx00020 | Exodeoxyribonuclease III; Identified by sequence similarity. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.628 |
Lxx04460 | nth | Lxx04460 | Lxx07190 | Exodeoxyribonuclease III; Identified by sequence similarity. | Adenine glycosylase; Identified by sequence similarity. | 0.573 |
Lxx04460 | polA | Lxx04460 | Lxx11410 | Exodeoxyribonuclease III; Identified by sequence similarity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.647 |
Lxx04460 | rsuA | Lxx04460 | Lxx05710 | Exodeoxyribonuclease III; Identified by sequence similarity. | RNA pseudouridine synthase; Identified by sequence similarity; Belongs to the pseudouridine synthase RsuA family. | 0.625 |
Lxx04460 | ung | Lxx04460 | Lxx18890 | Exodeoxyribonuclease III; Identified by sequence similarity. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.477 |
Lxx04460 | xthA | Lxx04460 | Lxx23390 | Exodeoxyribonuclease III; Identified by sequence similarity. | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.929 |
Lxx23380 | pyrE | Lxx23380 | Lxx23400 | Conserved hypothetical protein; Identified by sequence similarity. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.722 |
Lxx23380 | xthA | Lxx23380 | Lxx23390 | Conserved hypothetical protein; Identified by sequence similarity. | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.441 |
def | xthA | Lxx08610 | Lxx23390 | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.432 |
dnaN | Lxx04460 | Lxx00020 | Lxx04460 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.628 |
dnaN | nth | Lxx00020 | Lxx07190 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Adenine glycosylase; Identified by sequence similarity. | 0.502 |
dnaN | polA | Lxx00020 | Lxx11410 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
dnaN | ung | Lxx00020 | Lxx18890 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.658 |
dnaN | xthA | Lxx00020 | Lxx23390 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.628 |
murI | xthA | Lxx13590 | Lxx23390 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.594 |
nth | Lxx04460 | Lxx07190 | Lxx04460 | Adenine glycosylase; Identified by sequence similarity. | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.573 |
nth | dnaN | Lxx07190 | Lxx00020 | Adenine glycosylase; Identified by sequence similarity. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.502 |
nth | polA | Lxx07190 | Lxx11410 | Adenine glycosylase; Identified by sequence similarity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.403 |
nth | xthA | Lxx07190 | Lxx23390 | Adenine glycosylase; Identified by sequence similarity. | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.573 |
polA | Lxx04460 | Lxx11410 | Lxx04460 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Exodeoxyribonuclease III; Identified by sequence similarity. | 0.647 |