STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxAGlutaredoxin 1. (86 aa)    
Predicted Functional Partners:
KU46_1681
nrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit.
  
 0.968
KU46_1683
Ribonucleotide reductase, small chain family protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
  
0.805
secB
Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.703
secB-2
Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.703
grxD
Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.581
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.580
msrB
methionine-R-sulfoxide reductase.
  
 
 0.580
atpF
ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
  
    0.541
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
    
  0.506
KU46_641
Rhodanese-like domain protein.
  
    0.484
Your Current Organism:
Francisella philomiragia
NCBI taxonomy Id: 28110
Other names: ATCC 25015, CCUG 19700, CCUG 4992, CIP 82.98, DSM 7535, F. philomiragia, Francisella philomiragia subsp. philomiragia, Yersinia philomiragia, strain O#319L
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.