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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KU46_960GDSL-like Lipase/Acylhydrolase family protein. (293 aa)    
Predicted Functional Partners:
KU46_959
cobB/CobQ-like glutamine amidotransferase domain protein.
 
     0.813
KU46_957
SRP54-type, GTPase domain protein.
       0.752
KU46_958
parB_part: ParB/RepB/Spo0J family partition domain protein; Belongs to the ParB family.
       0.752
KU46_962
Helix-turn-helix domain protein.
       0.613
KU46_1792
Major Facilitator Superfamily protein.
  
     0.591
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.482
KU46_1067
Major Facilitator Superfamily protein.
  
     0.468
KU46_654
RNB domain protein.
  
     0.404
Your Current Organism:
Francisella philomiragia
NCBI taxonomy Id: 28110
Other names: ATCC 25015, CCUG 19700, CCUG 4992, CIP 82.98, DSM 7535, F. philomiragia, Francisella philomiragia subsp. philomiragia, Yersinia philomiragia, strain O#319L
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