STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (433 aa)    
Predicted Functional Partners:
bioD
ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.994
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.993
HQ47_05235
8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.965
HQ47_08075
Racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.925
bioF_1
2-amino-3-ketobutyrate CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.896
HQ47_01285
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.831
HQ47_01290
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.831
HQ47_01945
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.831
HQ47_06815
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.831
bioC
Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
 
 
 0.807
Your Current Organism:
Porphyromonas macacae
NCBI taxonomy Id: 28115
Other names: ATCC 33141, Bacteroides macacae, Bacteroides melaninogenicus macacae, Bacteroides melaninogenicus subsp. macacae, Bacteroides salivosus, CCUG 47703, DSM 20710, JCM 13914, NCTC 13100, P. macacae, Porphyromonas salivosa, Slots strain 7728-L6C, strain 7728-L6C
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