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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HQ47_03070Hypothetical protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (349 aa)    
Predicted Functional Partners:
aroA_2
Cytochrome C4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
HQ47_10545
Hypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.993
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 0.988
aroE
AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.986
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.979
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.966
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.797
HQ47_02630
Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.737
cobD-2
L-threonine-O-3-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.701
HQ47_07110
Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
  0.609
Your Current Organism:
Porphyromonas macacae
NCBI taxonomy Id: 28115
Other names: ATCC 33141, Bacteroides macacae, Bacteroides melaninogenicus macacae, Bacteroides melaninogenicus subsp. macacae, Bacteroides salivosus, CCUG 47703, DSM 20710, JCM 13914, NCTC 13100, P. macacae, Porphyromonas salivosa, Slots strain 7728-L6C, strain 7728-L6C
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