close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HQ47_03250Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)    
Predicted Functional Partners:
HQ47_03255
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
     0.859
HQ47_03245
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.631
HQ47_03890
uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.614
HQ47_04710
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.595
HQ47_04435
RagB/SusD family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.583
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.569
gyrA_1
DNA topoisomerase IV subunit A; Decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.543
HQ47_10370
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.515
HQ47_04455
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.478
HQ47_04895
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.478
Your Current Organism:
Porphyromonas macacae
NCBI taxonomy Id: 28115
Other names: ATCC 33141, Bacteroides macacae, Bacteroides melaninogenicus macacae, Bacteroides melaninogenicus subsp. macacae, Bacteroides salivosus, CCUG 47703, DSM 20710, JCM 13914, NCTC 13100, P. macacae, Porphyromonas salivosa, Slots strain 7728-L6C, strain 7728-L6C
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.