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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HQ47_07705Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (94 aa)    
Predicted Functional Partners:
HQ47_09640
Restriction endonuclease subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
 
 0.850
HQ47_07710
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.705
HQ47_03130
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.508
HQ47_10145
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.508
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.451
HQ47_01110
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.402
HQ47_06625
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.402
HQ47_08635
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.400
Your Current Organism:
Porphyromonas macacae
NCBI taxonomy Id: 28115
Other names: ATCC 33141, Bacteroides macacae, Bacteroides melaninogenicus macacae, Bacteroides melaninogenicus subsp. macacae, Bacteroides salivosus, CCUG 47703, DSM 20710, JCM 13914, NCTC 13100, P. macacae, Porphyromonas salivosa, Slots strain 7728-L6C, strain 7728-L6C
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