close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HQ47_08095Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (918 aa)    
Predicted Functional Partners:
HQ47_08090
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.845
HQ47_04495
SNF2/RAD54 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.737
HQ47_10625
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.652
HQ47_04435
RagB/SusD family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.648
HQ47_04455
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.648
HQ47_04710
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.648
HQ47_04895
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.648
HQ47_03055
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.565
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
   0.561
HQ47_01145
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.537
Your Current Organism:
Porphyromonas macacae
NCBI taxonomy Id: 28115
Other names: ATCC 33141, Bacteroides macacae, Bacteroides melaninogenicus macacae, Bacteroides melaninogenicus subsp. macacae, Bacteroides salivosus, CCUG 47703, DSM 20710, JCM 13914, NCTC 13100, P. macacae, Porphyromonas salivosa, Slots strain 7728-L6C, strain 7728-L6C
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.