STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfnBPutative HAD-hydrolase YfnB. (230 aa)    
Predicted Functional Partners:
tdk
Thymidine kinase.
 
  
  0.949
udk
Uridine kinase.
 
 
 0.921
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.921
deoD
Purine nucleoside phosphorylase DeoD-type.
 
 
 0.920
punA
Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.916
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
  0.912
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.911
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.910
pncC
Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family.
    
  0.910
pncB2
Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
 
 0.910
Your Current Organism:
Bacteroides ovatus
NCBI taxonomy Id: 28116
Other names: ATCC 8483, B. ovatus, BCRC 10623, Bacteroides fragilis subsp. ovatus, CCRC 10623, CCRC:10623, CCUG 4943, CIP 103756, JCM 5824, NCTC 11153, Pasteurella ovata, Pseudobacterium ovatum, bacterium NLAE-zl-C11, bacterium NLAE-zl-C34, bacterium NLAE-zl-C500, bacterium NLAE-zl-C57, bacterium NLAE-zl-H304, bacterium NLAE-zl-H361, bacterium NLAE-zl-H59, bacterium NLAE-zl-H73
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