node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
deoD | punA | Bovatus_04744 | Bovatus_02451 | Purine nucleoside phosphorylase DeoD-type. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.920 |
deoD | tdk | Bovatus_04744 | Bovatus_02336 | Purine nucleoside phosphorylase DeoD-type. | Thymidine kinase. | 0.923 |
deoD | udk | Bovatus_04744 | Bovatus_00077 | Purine nucleoside phosphorylase DeoD-type. | Uridine kinase. | 0.916 |
deoD | yfnB | Bovatus_04744 | Bovatus_02332 | Purine nucleoside phosphorylase DeoD-type. | Putative HAD-hydrolase YfnB. | 0.920 |
guaB | pncC | Bovatus_03970 | Bovatus_00722 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.469 |
guaB | punA | Bovatus_03970 | Bovatus_02451 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.517 |
guaB | purA | Bovatus_03970 | Bovatus_01903 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.994 |
guaB | udk | Bovatus_03970 | Bovatus_00077 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Uridine kinase. | 0.430 |
guaB | xpt | Bovatus_03970 | Bovatus_00275 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.970 |
guaB | yfnB | Bovatus_03970 | Bovatus_02332 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Putative HAD-hydrolase YfnB. | 0.921 |
nadD | pncB2 | Bovatus_01959 | Bovatus_01936 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.963 |
nadD | pncC | Bovatus_01959 | Bovatus_00722 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.976 |
nadD | yfnB | Bovatus_01959 | Bovatus_02332 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative HAD-hydrolase YfnB. | 0.911 |
pncB2 | nadD | Bovatus_01936 | Bovatus_01959 | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.963 |
pncB2 | pncC | Bovatus_01936 | Bovatus_00722 | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.969 |
pncB2 | punA | Bovatus_01936 | Bovatus_02451 | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.916 |
pncB2 | yfnB | Bovatus_01936 | Bovatus_02332 | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Putative HAD-hydrolase YfnB. | 0.910 |
pncC | guaB | Bovatus_00722 | Bovatus_03970 | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.469 |
pncC | nadD | Bovatus_00722 | Bovatus_01959 | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.976 |
pncC | pncB2 | Bovatus_00722 | Bovatus_01936 | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.969 |