STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (718 aa)    
Predicted Functional Partners:
rnd
Ribonuclease D.
   
 
 0.921
nudF
ADP-ribose pyrophosphatase.
   
 0.883
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
    
 0.774
ALJ47753.1
Pyridoxamine 5'-phosphate oxidase.
       0.755
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
 
 0.688
ALJ47836.1
Putative TrmH family tRNA/rRNA methyltransferase.
 
 
 0.652
ALJ46039.1
Putative TrmH family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
 
 0.630
aviRb
23S rRNA (uridine(2479)-2'-O)-methyltransferase.
 
 
 0.624
ALJ49403.1
ATP-dependent helicase HepA.
  
 0.621
cca
Multifunctional CCA protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
 
 0.604
Your Current Organism:
Bacteroides ovatus
NCBI taxonomy Id: 28116
Other names: ATCC 8483, B. ovatus, BCRC 10623, Bacteroides fragilis subsp. ovatus, CCRC 10623, CCRC:10623, CCUG 4943, CIP 103756, JCM 5824, NCTC 11153, Pasteurella ovata, Pseudobacterium ovatum, bacterium NLAE-zl-C11, bacterium NLAE-zl-C34, bacterium NLAE-zl-C500, bacterium NLAE-zl-C57, bacterium NLAE-zl-H304, bacterium NLAE-zl-H361, bacterium NLAE-zl-H59, bacterium NLAE-zl-H73
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