STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
entCIsochorismate synthase EntC. (371 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 
 0.997
menB
1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.974
trpG
Anthranilate synthase component 2.
 
 
 0.942
ykfB
L-Ala-D/L-Glu epimerase.
 
   
 0.924
menE
2-succinylbenzoate--CoA ligase.
 
   
 0.914
yidA_2
Sugar phosphatase YidA.
 
  
 0.909
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.902
aroF
Phospho-2-dehydro-3-deoxyheptonate aldolase.
  
 
 0.898
trpE
Anthranilate synthase component 1.
 
  
0.895
hisC_1
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.812
Your Current Organism:
Bacteroides ovatus
NCBI taxonomy Id: 28116
Other names: ATCC 8483, B. ovatus, BCRC 10623, Bacteroides fragilis subsp. ovatus, CCRC 10623, CCRC:10623, CCUG 4943, CIP 103756, JCM 5824, NCTC 11153, Pasteurella ovata, Pseudobacterium ovatum, bacterium NLAE-zl-C11, bacterium NLAE-zl-C34, bacterium NLAE-zl-C500, bacterium NLAE-zl-C57, bacterium NLAE-zl-H304, bacterium NLAE-zl-H361, bacterium NLAE-zl-H59, bacterium NLAE-zl-H73
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