node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SJZ85579.1 | SKA05376.1 | SAMN02745108_01785 | SAMN02745108_02358 | Pyridoxine kinase; Belongs to the pyridoxine kinase family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.584 |
SJZ85579.1 | pdxS | SAMN02745108_01785 | SAMN02745108_01614 | Pyridoxine kinase; Belongs to the pyridoxine kinase family. | Pyridoxal 5'-phosphate synthase pdxS subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.590 |
SJZ85579.1 | pdxT | SAMN02745108_01785 | SAMN02745108_01615 | Pyridoxine kinase; Belongs to the pyridoxine kinase family. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.583 |
SJZ85579.1 | thiC | SAMN02745108_01785 | SAMN02745108_02356 | Pyridoxine kinase; Belongs to the pyridoxine kinase family. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.499 |
SKA05361.1 | SKA05376.1 | SAMN02745108_02357 | SAMN02745108_02358 | Hypothetical protein. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.773 |
SKA05361.1 | thiC | SAMN02745108_02357 | SAMN02745108_02356 | Hypothetical protein. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.773 |
SKA05376.1 | SJZ85579.1 | SAMN02745108_02358 | SAMN02745108_01785 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxine kinase; Belongs to the pyridoxine kinase family. | 0.584 |
SKA05376.1 | SKA05361.1 | SAMN02745108_02358 | SAMN02745108_02357 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hypothetical protein. | 0.773 |
SKA05376.1 | pdxS | SAMN02745108_02358 | SAMN02745108_01614 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxal 5'-phosphate synthase pdxS subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.605 |
SKA05376.1 | pdxT | SAMN02745108_02358 | SAMN02745108_01615 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.597 |
SKA05376.1 | rsgA | SAMN02745108_02358 | SAMN02745108_02125 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Ribosome biogenesis GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.548 |
SKA05376.1 | thiC | SAMN02745108_02358 | SAMN02745108_02356 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.998 |
SKA05376.1 | thiE | SAMN02745108_02358 | SAMN02745108_00605 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
SKA05376.1 | thiL | SAMN02745108_02358 | SAMN02745108_01112 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.618 |
SKA05376.1 | thiM | SAMN02745108_02358 | SAMN02745108_02734 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.987 |
SKA05376.1 | truA | SAMN02745108_02358 | SAMN02745108_01778 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | tRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.642 |
pdxS | SJZ85579.1 | SAMN02745108_01614 | SAMN02745108_01785 | Pyridoxal 5'-phosphate synthase pdxS subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Pyridoxine kinase; Belongs to the pyridoxine kinase family. | 0.590 |
pdxS | SKA05376.1 | SAMN02745108_01614 | SAMN02745108_02358 | Pyridoxal 5'-phosphate synthase pdxS subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.605 |
pdxS | pdxT | SAMN02745108_01614 | SAMN02745108_01615 | Pyridoxal 5'-phosphate synthase pdxS subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.999 |
pdxT | SJZ85579.1 | SAMN02745108_01615 | SAMN02745108_01785 | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | Pyridoxine kinase; Belongs to the pyridoxine kinase family. | 0.583 |