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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (493 aa)    
Predicted Functional Partners:
KXO17564.1
glutamine--tRNA ligase; KEGG: pmz:HMPREF0659_A6665 7.6e-289 glnS; glutamine--tRNA ligase K01886; Psort location: Cytoplasmic, score: 9.97.
 
 0.989
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 0.980
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.945
argS
arginine--tRNA ligase; KEGG: pmz:HMPREF0659_A6251 5.1e-292 argS; arginine--tRNA ligase K01887; Psort location: Cytoplasmic, score: 9.97.
  
 0.941
leuS
leucine--tRNA ligase; KEGG: pmz:HMPREF0659_A5028 0. leuS; leucine--tRNA ligase K01869; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.905
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.900
asnS
asparagine--tRNA ligase; KEGG: pdn:HMPREF9137_0245 5.1e-228 asnS; asparagine--tRNA ligase K01893; Psort location: Cytoplasmic, score: 10.00.
  
 0.888
lysS
lysine--tRNA ligase; KEGG: pmz:HMPREF0659_A6046 3.1e-292 lysS; lysine--tRNA ligase K04567; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.865
KXO18468.1
Hypothetical protein; Psort location: Periplasmic, score: 9.84.
       0.839
pheT
KEGG: pmz:HMPREF0659_A6941 0. pheT; phenylalanine--tRNA ligase, beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.768
Your Current Organism:
Prevotella bivia
NCBI taxonomy Id: 28125
Other names: ATCC 29303, Bacteroides bivius, CCUG 9557, CIP 105105, DSM 20514, JCM 6331, LMG 6452, LMG:6452, NCTC 11156, P. bivia, VPI 6822, strain 653C, strain JCVIHMP010
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