STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXO16642.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (195 aa)    
Predicted Functional Partners:
KXO18360.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pdn:HMPREF9137_0626 0. DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.778
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
 
 0.778
KXO17746.1
Putative translation elongation factor G; KEGG: bnm:BALAC2494_01437 2.4e-63 Protein-synthesizing GTPase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.750
KXO17751.1
RteC protein; Psort location: Cytoplasmic, score: 8.96.
  
     0.727
KXO16641.1
Hypothetical protein.
       0.718
KXO15189.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
     0.674
KXO14915.1
Hypothetical protein; KEGG: edi:EDI_048910 1.4e-05 intracellular protein transport protein USO1; Psort location: Periplasmic, score: 9.51.
  
     0.639
KXO15188.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
     0.627
KXO15158.1
RHS repeat protein.
  
     0.621
KXO17747.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: gfo:GFO_3052 4.1e-51 two-component system sensor histidine kinase/response regulator hybrid K00936; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.618
Your Current Organism:
Prevotella bivia
NCBI taxonomy Id: 28125
Other names: ATCC 29303, Bacteroides bivius, CCUG 9557, CIP 105105, DSM 20514, JCM 6331, LMG 6452, LMG:6452, NCTC 11156, P. bivia, VPI 6822, strain 653C, strain JCVIHMP010
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.