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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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KXO14680.1acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (257 aa)    
Predicted Functional Partners:
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
 
 0.998
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
 
 0.976
KXO17983.1
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.924
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
 0.840
miaA-2
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.818
KXO17905.1
KEGG: pmz:HMPREF0659_A5505 1.0e-128 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97.
    
  0.809
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.803
KXO17320.1
KEGG: pmz:HMPREF0659_A5655 1.2e-141 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.786
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.743
KXO17485.1
KEGG: pmz:HMPREF0659_A6183 2.0e-132 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12.
 
  
 0.707
Your Current Organism:
Prevotella bivia
NCBI taxonomy Id: 28125
Other names: ATCC 29303, Bacteroides bivius, CCUG 9557, CIP 105105, DSM 20514, JCM 6331, LMG 6452, LMG:6452, NCTC 11156, P. bivia, VPI 6822, strain 653C, strain JCVIHMP010
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