| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA32954.1 | KXA33401.1 | HMPREF3226_02573 | HMPREF3226_02468 | KEGG: pit:PIN17_A1263 2.5e-68 methyladenine glycosylase; K01246 DNA-3-methyladenine glycosylase I. | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.771 |
| KXA32954.1 | polA | HMPREF3226_02573 | HMPREF3226_02765 | KEGG: pit:PIN17_A1263 2.5e-68 methyladenine glycosylase; K01246 DNA-3-methyladenine glycosylase I. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.501 |
| KXA33399.1 | KXA33400.1 | HMPREF3226_02466 | HMPREF3226_02467 | FMN-binding domain protein; KEGG: ssm:Spirs_3327 2.5e-05 flavocytochrome C; K00244 fumarate reductase flavoprotein subunit. | Hypothetical protein. | 0.741 |
| KXA33399.1 | KXA33401.1 | HMPREF3226_02466 | HMPREF3226_02468 | FMN-binding domain protein; KEGG: ssm:Spirs_3327 2.5e-05 flavocytochrome C; K00244 fumarate reductase flavoprotein subunit. | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.455 |
| KXA33400.1 | KXA33399.1 | HMPREF3226_02467 | HMPREF3226_02466 | Hypothetical protein. | FMN-binding domain protein; KEGG: ssm:Spirs_3327 2.5e-05 flavocytochrome C; K00244 fumarate reductase flavoprotein subunit. | 0.741 |
| KXA33400.1 | KXA33401.1 | HMPREF3226_02467 | HMPREF3226_02468 | Hypothetical protein. | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.472 |
| KXA33401.1 | KXA32954.1 | HMPREF3226_02468 | HMPREF3226_02573 | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | KEGG: pit:PIN17_A1263 2.5e-68 methyladenine glycosylase; K01246 DNA-3-methyladenine glycosylase I. | 0.771 |
| KXA33401.1 | KXA33399.1 | HMPREF3226_02468 | HMPREF3226_02466 | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | FMN-binding domain protein; KEGG: ssm:Spirs_3327 2.5e-05 flavocytochrome C; K00244 fumarate reductase flavoprotein subunit. | 0.455 |
| KXA33401.1 | KXA33400.1 | HMPREF3226_02468 | HMPREF3226_02467 | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Hypothetical protein. | 0.472 |
| KXA33401.1 | KXA33402.1 | HMPREF3226_02468 | HMPREF3226_02469 | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Putative DNA-binding protein. | 0.428 |
| KXA33401.1 | KXA40736.1 | HMPREF3226_02468 | HMPREF3226_00996 | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 0. UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | 0.404 |
| KXA33401.1 | KXA40749.1 | HMPREF3226_02468 | HMPREF3226_01010 | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.629 |
| KXA33401.1 | polA | HMPREF3226_02468 | HMPREF3226_02765 | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.511 |
| KXA33402.1 | KXA33401.1 | HMPREF3226_02469 | HMPREF3226_02468 | Putative DNA-binding protein. | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.428 |
| KXA33402.1 | KXA40736.1 | HMPREF3226_02469 | HMPREF3226_00996 | Putative DNA-binding protein. | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 0. UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | 0.569 |
| KXA40736.1 | KXA33401.1 | HMPREF3226_00996 | HMPREF3226_02468 | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 0. UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.404 |
| KXA40736.1 | KXA33402.1 | HMPREF3226_00996 | HMPREF3226_02469 | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 0. UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | Putative DNA-binding protein. | 0.569 |
| KXA40736.1 | KXA40749.1 | HMPREF3226_00996 | HMPREF3226_01010 | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 0. UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.908 |
| KXA40736.1 | polA | HMPREF3226_00996 | HMPREF3226_02765 | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 0. UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.887 |
| KXA40749.1 | KXA33401.1 | HMPREF3226_01010 | HMPREF3226_02468 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.629 |
