Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
 0.999
KXA35393.1
KEGG: pit:PIN17_A1098 7.1e-199 AICARFT/IMPCHase bienzyme; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97.
  
 0.981
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.975
KXA35369.1
KEGG: pit:PIN17_A1996 3.0e-88 MGS-like domain protein; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97.
  
 0.960
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.944
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 
 0.940
KXA35389.1
Ser/Thr phosphatase family protein; KEGG: bvu:BVU_0146 1.2e-77 5'-nucleotidase; K01081 5'-nucleotidase.
   
 0.937
rpsB
Ribosomal protein S2; KEGG: apb:SAR116_0519 5.5e-57 30S ribosomal protein S2 K02967; Psort location: Cytoplasmic, score: 9.97; Belongs to the universal ribosomal protein uS2 family.
   
 
 0.933
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.932
KXA37792.1
Putative arabinose 5-phosphate isomerase; KEGG: pit:PIN17_A1816 2.8e-149 sugar isomerase, KpsF/GutQ family; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily.
    
 0.931
Your Current Organism:
Prevotella corporis
NCBI taxonomy Id: 28128
Other names: ATCC 33547, Bacteroides corporis, CIP 105107, DSM 18810, JCM 8529, NCTC 13065, P. corporis, VPI 9342, strain Lambe 532-70A
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