Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXA33418.1KEGG: pit:PIN17_A0096 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. (727 aa)    
Predicted Functional Partners:
KXA43045.1
KEGG: pit:PIN17_A1673 9.1e-254 RecQ familyATP-dependent DNA helicase K03654; Psort location: Cytoplasmic, score: 9.97.
  
  
 
0.937
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.896
KXA39538.1
DEAD/DEAH box helicase; KEGG: pdn:HMPREF9137_0656 4.5e-284 putative cold-shock DEAD-box protein A; K05592 ATP-dependent RNA helicase DeaD; Psort location: Cytoplasmic, score: 9.97.
  
 
0.893
KXA40736.1
UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 0. UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97.
  
 0.839
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 
 0.804
KXA40901.1
KEGG: pmz:HMPREF0659_A6764 0. putative ATP-dependent helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.94.
  
 0.769
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.750
recA-2
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.750
KXA40749.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.746
KXA37917.1
Protein, SNF2 family; KEGG: tva:TVAG_308180 8.5e-23 SNF2 family N-terminal domain containing protein; K14437 chromodomain-helicase-DNA-binding protein 7; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.727
Your Current Organism:
Prevotella corporis
NCBI taxonomy Id: 28128
Other names: ATCC 33547, Bacteroides corporis, CIP 105107, DSM 18810, JCM 8529, NCTC 13065, P. corporis, VPI 9342, strain Lambe 532-70A
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