Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
APW33377.1YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
    0.950
nadD
Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.815
APW33374.1
Lipopolysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.630
APW33378.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.509
APW34239.1
Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.497
CinA
Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
 
     0.470
rpoN
RNA polymerase sigma-54 factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.411
tsaB
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.403
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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