| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APW34020.1 | PunA | BWX40_03760 | BWX40_07375 | Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
| APW34020.1 | adk | BWX40_03760 | BWX40_03770 | Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.614 |
| APW34020.1 | hpt | BWX40_03760 | BWX40_03775 | Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.639 |
| APW34020.1 | nnrD | BWX40_03760 | BWX40_03780 | Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...] | 0.590 |
| APW34020.1 | obg | BWX40_03760 | BWX40_03765 | Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.820 |
| PunA | APW34020.1 | BWX40_07375 | BWX40_03760 | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.902 |
| PunA | guaA | BWX40_07375 | BWX40_04925 | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.636 |
| PunA | hpt | BWX40_07375 | BWX40_03775 | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.659 |
| adk | APW34020.1 | BWX40_03770 | BWX40_03760 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.614 |
| adk | guaA | BWX40_03770 | BWX40_04925 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.547 |
| adk | hpt | BWX40_03770 | BWX40_03775 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.985 |
| adk | nnrD | BWX40_03770 | BWX40_03780 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...] | 0.686 |
| adk | obg | BWX40_03770 | BWX40_03765 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.629 |
| adk | polA | BWX40_03770 | BWX40_01195 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.503 |
| ftsH | hpt | BWX40_08715 | BWX40_03775 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.727 |
| ftsH | polA | BWX40_08715 | BWX40_01195 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.570 |
| gap | guaA | BWX40_04910 | BWX40_04925 | Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.536 |
| gap | hpt | BWX40_04910 | BWX40_03775 | Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.523 |
| gap | polA | BWX40_04910 | BWX40_01195 | Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.569 |
| guaA | PunA | BWX40_04925 | BWX40_07375 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.636 |
