STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APW34240.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)    
Predicted Functional Partners:
APW34239.1
Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.953
APW34241.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.888
secG
Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
 
     0.810
APW35338.1
DUF490 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.769
APW34406.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.758
APW35553.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.749
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.738
APW34918.1
Nucleic acid-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.708
APW34899.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.683
APW35439.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.663
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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